Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315400 | 1.00 | PPARA (0.53) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL8984893 | 0.89 | RXRA (0.56) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL3667760 | 0.87 | LMNA (0.59) | PPARAPPARGTHRATHRBLTB4R | |
| SCHEMBL5138907 | 0.84 | PTPN11 (0.66) | PTPN1PTPN6PTPN11THRATHRB | |
| SCHEMBL5093658 | 0.84 | PTPN11 (0.66) | PTPN1PTPN6PTPN11THRATHRB | |
| SCHEMBL28381703 | 0.84 | HTT (0.59) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL7733989 | 0.83 | THRA (0.56) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL20631419 | 0.83 | TRPV1 (0.67) | CNR2 | |
| SCHEMBL8163368 | 0.83 | PPARA (0.59) | PPARAPPARGPTPN1PTPN6PTPN11 | |
| SCHEMBL3667217 | 0.82 | LMNA (0.65) | PPARAPPARGLTB4RPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307229-A | CORD FACTOR, ANTITUMOR AGENTS | LIAV AVRAHAM | 1981-12-22 | — | — | US | claimed |
| US-4307229-A | CORD FACTOR, ANTITUMOR AGENTS | LIAV AVRAHAM | 1981-12-22 | — | — | US | disclosed |