Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693650 | 0.93 | LMNA (0.60) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL3667760 | 0.92 | LMNA (0.59) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL8984884 | 0.89 | LMNA (0.63) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL10467868 | 0.89 | HDAC1 (0.52) | LMNAL3MBTL1HDAC1HDAC2PPARG | |
| SCHEMBL2840795 | 0.87 | FFAR4 (0.55) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL6693290 | 0.87 | LMNA (0.60) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL3974023 | 0.86 | FFAR4 (0.51) | LMNAL3MBTL1FFAR4FFAR1HDAC1 | |
| SCHEMBL30159686 | 0.84 | ALDH1A1 (0.53) | LMNAL3MBTL1PPARGMAPTHSD17B10 | |
| SCHEMBL28669480 | 0.84 | ALDH1A1 (0.53) | LMNAL3MBTL1PPARGMAPTHSD17B10 | |
| SCHEMBL9679355 | 0.83 | RXRA (0.63) | LMNAL3MBTL1FFAR4FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | BIEDIGER RONALD J | 2006-12-07 | — | — | US | disclosed |
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | VCAM1, ICAM1, ITGA1 | LMNA 1820/4885L3MBTL1 3947/4885FFAR4 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.