Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14549464 | 0.92 | ALDH1A1 (0.40) | MAPTTSHRALDH1A1PPARGCHRM1 | |
| SCHEMBL10317053 | 0.90 | MAPT (0.53) | MAPTPPARGCHRM1HTR2AMCHR1 | |
| SCHEMBL21770490 | 0.86 | MAPT (0.36) | MAPTTSHRPPARGCHRM1HTR2A | |
| SCHEMBL15014122 | 0.80 | ADRA2A (0.50) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL6856568 | 0.79 | CYP4F2 (0.49) | CYP3A4L3MBTL1MMP14LTA4H | |
| SCHEMBL20005167 | 0.78 | MAPT (0.41) | MAPTTSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL19822987 | 0.77 | MMP14 (0.42) | MAPTTSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL165131 | 0.77 | ALDH1A1 (0.64) | MAPTTSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11310810 | 0.77 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL8499036 | 0.76 | THRA (0.46) | MAPTALDH1A1CYP3A4CHRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018848-B2 | Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. | ORÉAL L (FR) | 2016-08-31 | — | — | EP | disclosed |
| US-8784775-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2014-07-22 | — | — | US | disclosed |
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | disclosed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | disclosed |
| EP-2018848-A2 | Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | KRT18, S100A4, S100P | MAPT 220/4885TSHR 3685/4885ALDH1A1 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.