Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1131532

CN(C)CCO.O=C(O)C(F)(F)F

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.57
RAD52 P43351 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
APAF1 O14727 1/20 0.36
CASP7 P55210 1/20 0.36
CASP6 P55212 1/20 0.36
CASP8 Q14790 1/20 0.36
CHRM2 P08172 3/20 0.35
CHRM4 P08173 3/20 0.35
CHRM5 P08912 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM3 P20309 3/20 0.35
OPRM1 P35372 2/20 0.35
DRD3 P35462 2/20 0.35
DRD4 P21917 1/20 0.35
CACNA1B Q00975 3/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
DRD2 P14416 1/20 0.32
HTR5A P47898 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3202270 0.86 MAPT (0.38) MAPTRAD52L3MBTL1APAF1CASP7
Dimethylaminoethanol SCHEMBL1131211 0.85 MAPT (0.50) MAPTRAD52L3MBTL1APAF1CASP7
Dimethylaminoethanol SCHEMBL1131226 0.82 MAPT (0.75) MAPTCHRM2CHRM4CHRM5CHRM1
Dimethylaminoethanol SCHEMBL1131465 0.82 MAPT (0.75) MAPTCHRM2CHRM4CHRM5CHRM1
Dimethylaminoethanol SCHEMBL1131545 0.81 THRB (0.48) MAPTRAD52L3MBTL1APAF1CASP7
Trifluoroacetic Acid SCHEMBL31657045 0.81 ALDH1A1 (0.52) RAD52L3MBTL1APAF1CASP7CASP6
Trifluoroacetic Acid SCHEMBL2870725 0.81 MLYCD (0.39) RAD52L3MBTL1APAF1CASP7CASP6
Trolamine SCHEMBL5874602 0.80 ALOX15 (0.38) MAPTCHRM2DRD3MEN1LMNA
Dimethylaminoethanol SCHEMBL358310 0.79 MAPT (0.71) MAPTCHRM2CHRM4CHRM5CHRM1
Dimethylaminoethanol SCHEMBL1131507 0.79 MAPT (0.71) MAPTCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US claimed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP claimed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
CN-117142514-A PF 6-intercalated layered Zn-Al-LDH and preparation method thereof 河南农业大学 2023-12-01 CN disclosed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20080191170-A1 Use of Ionic Liquids CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2008-08-14 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed
EP-1804969-A2 USE OF IONIC LIQUIDS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2007-07-11 EP disclosed
WO-2006038013-A2 USE OF IONIC LIQUIDS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2006-04-13 WO disclosed