Sugi Predict

Sugi Predict / Compounds / SCHEMBL1132530

SCHEMBL1132530

SCHEMBL1132530

NC(CC1=C[N]c2ccccc21)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.50
▸ ALPI P09923 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ PTGS1 P23219 1/20 0.50
▸ XIAP P98170 1/20 0.50
▸ CYP1A2 P05177 2/20 0.42
▸ SLC1A3 P43003 1/20 0.41
▸ SLC1A2 P43004 1/20 0.41
▸ SLC1A1 P43005 1/20 0.41
▸ MAPK1 P28482 1/20 0.40
▸ NOS3 P29474 2/20 0.40
▸ NOS1 P29475 2/20 0.40
▸ NOS2 P35228 2/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MPO P05164 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL825550 0.69 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL825551 0.69 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL16398196 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL43671 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8119 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL16398197 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL837632 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.68 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110257194-B Handmade soap with shortened saponification time and preparation method thereof 广东石油化工学院 2020-12-04 — — CN claimed
WO-2023095139-A1 VERSATILE PEROXIDASES AND USES THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-06-01 — — WO disclosed
CN-110257194-B Handmade soap with shortened saponification time and preparation method thereof 广东石油化工学院 2020-12-04 — — CN disclosed
US-10696954-B2 Hybrid peroxidases with enhanced activity and stability THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-06-30 — — US disclosed
US-20190241875-A1 HYBRID PEROXIDASES WITH ENHANCED ACTIVITY AND STABILITY UNITED STATES DEPARTMENT OF ENERGY 2019-08-08 — — US disclosed
US-20140100217-A1 STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THEIR USE FORSCHUNGSVERBUND BERLIN E.V. (DE) 2014-04-10 — — US disclosed
US-8551719-B1 Endotoxin detection method HYGLOS INVEST GMBH (DE) 2013-10-08 — — US disclosed
US-20130244224-A1 ENDOTOXIN DETECTION METHOD HYGLOS INVEST GMBH (DE) 2013-09-19 — — US disclosed
US-20130245275-A1 PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAET BONN (DE) 2013-09-19 — — US disclosed
EP-2625168-A1 PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES Rheinische Friedrich-Wilhelms-Universität (DE) 2013-08-14 — — EP disclosed
US-8163788-B2 Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT BONN (DE) 2012-04-24 — — US disclosed
WO-2012045734-A1 PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) 2012-04-12 — — WO disclosed
US-20110053188-A1 ENDOTOXIN DETECTION METHOD HYGLOS INVEST GMBH (DE) 2011-03-03 — — US disclosed
WO-2011020849-A1 CYTOHESIN INHIBITORS RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) 2011-02-24 — — WO disclosed
EP-2286808-A1 Cytohesin inhibitors Rheinische Friedrich-Wilhelms Universität (DE) 2011-02-23 — — EP disclosed
US-7858299-B2 Method for detecting and for removing endotoxin HYGLOS INVEST GMBH (DE) 2010-12-28 — — US disclosed
US-20100028857-A1 Method for Detecting and for Removing Endotoxin PROFOS AG (DE) 2010-02-04 — — US disclosed
US-7585620-B2 Method for identifying and for extracting endotoxin PROFOS AG (DE) 2009-09-08 — — US disclosed
US-20090105286-A1 Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT (DE) 2009-04-23 — — US disclosed
US-20060172281-A1 Method for identifying and for extracting endotoxin HYGLOS INVEST GMBH (DE) 2006-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140100217-A1 STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THEIR USE NPY1R, NPR1, NPY2R SLC7A5 451/4885ALPI 4719/4885PKM 1911/4885
US-20090105286-A1 Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors CYTH2, CYTH3, ENTPD5 SLC7A5 577/4885ALPI 4193/4885PKM 4799/4885
US-20130245275-A1 PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES QDPR, DDT, DDC SLC7A5 1171/4885ALPI 4433/4885PKM 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.