Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 4/20 | 0.53 |
| ▸ | BCR | P11274 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605045 | 0.84 | ABL1 (0.55) | ABL1BCRKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4052204 | 0.84 | FYN (0.57) | MAPTKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL420705 | 0.82 | KDM4E (0.55) | MAPTABL1BCRKDM4EALDH1A1 | |
| Acetic Acid SCHEMBL27477993 | 0.82 | KDM4E (0.52) | MAPTABL1BCRKDM4EALDH1A1 | |
| SCHEMBL3081682 | 0.81 | CHEK1 (0.62) | MAPTABL1BCRKDM4EALDH1A1 | |
| SCHEMBL1020361 | 0.81 | ABL1 (0.53) | ABL1BCRKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7336149 | 0.80 | MAPT (0.66) | MAPTABL1BCRKDM4EALDH1A1 | |
| SCHEMBL30887807 | 0.80 | KDM4E (0.53) | MAPTSMN1; SMN2ABL1BCRKDM4E | |
| SCHEMBL13689286 | 0.80 | SLC6A2 (0.54) | ABL1BCRKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3193250 | 0.80 | MAPT (0.66) | MAPTABL1BCRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303543-A1 | NOVEL STIRIPENTOL DERIVATIVE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2023-09-28 | — | — | US | disclosed |
| US-20230303543-A1 | NOVEL STIRIPENTOL DERIVATIVE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2023-09-28 | — | — | US | disclosed |
| CN-113230240-B | 1,3-diphenylprop-2-en-1-one derivative and application thereof | 广州医科大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-113230240-A | 1, 3-diphenylprop-2-en-1-one derivative and application thereof | 广州医科大学 | 2021-08-10 | — | — | CN | disclosed |
| US-9845317-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2016-12-29 | — | — | US | disclosed |
| EP-1306131-B1 | Cross-coupling process using a catalyst comprising a cyclic nitrogen ligand | SUMITOMO CHEMICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-9328102-B2 | Slow release of organoboronic acids in cross-coupling reactions | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| EP-2287141-B1 | METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-10-21 | — | — | EP | disclosed |
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | NATIONAL SCIENCE FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-20040048858-A1 | Chalcone derivatives and their use to treat diseases | CRABTREE ACQUISITION CO, LLC | 2004-03-11 | — | — | US | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| CN-1432140-A | Solid imaging compositions for making polypropylene-like articles | DSM NV (NL) | 2003-07-23 | — | — | CN | disclosed |
| WO-2003053368-A2 | CHALCONE DERIVATIVES AND THEIR USE TO TREAT DISEASES | ATHEROGENICS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-4994623-A | Process for producing thioalkyl or thioarylphenones | HOECHST CELANESE CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0140540-B1 | PHOTOCHROMIC COMPOUNDS AND THEIR USES IN PHOTOREACTIVE LENSES | THE PLESSEY COMPANY plc (GB) | 1990-05-09 | — | — | EP | disclosed |
| EP-0361790-A1 | Process for producing alkylthio or arylthiophenones | HOECHST CELANESE CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4685783-A | Polychromic tetracyclo-spiro-adamatylidene derivatives, and polychromic lens incorporating said compounds | THE PLESSEY COMPANY P.L.C. (GB) | 1987-08-11 | — | — | US | disclosed |
| EP-0140540-A2 | Photochromic compounds and their uses in photoreactive lenses | THE PLESSEY COMPANY plc (GB) | 1985-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246905-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | MAPT 3222/4885SMN1; SMN2 537/4885ABL1 392/4885 |
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | MAPT 4796/4885SMN1; SMN2 990/4885ABL1 834/4885 |
| US-20160376260-A1 | Slow Release of Organoboronic Acids in Cross-Coupling Reactions | BRS3, CD79B, GRB2 | MAPT 3222/4885SMN1; SMN2 537/4885ABL1 392/4885 |
| US-20230303543-A1 | NOVEL STIRIPENTOL DERIVATIVE AND USE THEREOF | LDHA, SDHA, LDHB | MAPT 1699/4885SMN1; SMN2 1819/4885ABL1 4032/4885 |
| US-20040048858-A1 | Chalcone derivatives and their use to treat diseases | CYP46A1, CYP11B1, HSD17B7 | MAPT 1460/4885SMN1; SMN2 2245/4885ABL1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.