SCHEMBL11330833

SCHEMBL11330833

C=CCC(=C1C=CC=C1)c1ccc(Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
GSK3B P49841 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
ATM Q13315 2/20 0.34
TSHR P16473 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALOX15 P16050 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11326810 0.84 MAOA (0.33) CES2CES1MAOAMAOBCA1
SCHEMBL11327194 0.75 HDAC3 (0.41) BCL2L1CES2CES1GSK3BATM
SCHEMBL7034834 0.72 MAOA (0.52) CES2CES1GSK3BMAOAMAOB
SCHEMBL11316612 0.72 HDAC3 (0.39) BCL2L1CES2CES1GSK3BATM
SCHEMBL3415923 0.71 GSK3B (0.57) CES2CES1GSK3BATMTSHR
SCHEMBL401165 0.71 CES2 (0.46) CES2CES1GSK3BATMTSHR
SCHEMBL16411470 0.69 L3MBTL1 (0.56) CES2CES1TSHRL3MBTL1ALOX15
SCHEMBL4389892 0.69 AKT1 (0.34) ALDH1A1LMNAMAPTMAPK1
SCHEMBL28552572 0.68 LMNA (0.36) CES2CES1GSK3BMAOAMAOB
SCHEMBL28552571 0.68 LMNA (0.36) CES2CES1GSK3BMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4264336-A FOR IMPROVING THE OCTANE QUALITY OF UNLEADED GASOLINE PHILLIPS PETROLEUM COMPANY (US) 1981-04-28 US disclosed