Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178221 | 0.86 | L3MBTL1 (0.47) | L3MBTL1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11352659 | 0.83 | CA2 (0.36) | L3MBTL1IDO1LMNASMN1; SMN2 | |
| SCHEMBL11351610 | 0.83 | L3MBTL1 (0.45) | L3MBTL1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11174291 | 0.82 | NPC1 (0.42) | L3MBTL1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11347085 | 0.82 | L3MBTL1 (0.35) | L3MBTL1IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11351617 | 0.82 | RAB9A (0.41) | L3MBTL1IDO1LMNAALDH1A1NPC1 | |
| Dimethylamine SCHEMBL11347087 | 0.80 | ALDH1A1 (0.42) | L3MBTL1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11343239 | 0.76 | ANPEP (0.39) | IDO1LMNAALDH1A1MAPTTP53 | |
| SCHEMBL12300247 | 0.75 | — | — | |
| SCHEMBL11346420 | 0.74 | SMN1; SMN2 (0.42) | L3MBTL1IDO1LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |