Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344377 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HPGDPOLBRECQL | |
| SCHEMBL2910158 | 0.82 | BRD4 (0.45) | ALDH1A1SMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3255431 | 0.79 | PGR (0.50) | ALDH1A1SMN1; SMN2HPGDRECQL | |
| SCHEMBL11561400 | 0.78 | GAA (0.46) | ALDH1A1SMN1; SMN2HPGDPOLBRECQL | |
| SCHEMBL1530140 | 0.78 | SLC6A2 (0.41) | ALDH1A1SMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3248027 | 0.77 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HPGDPOLBCHEK1 | |
| SCHEMBL11556259 | 0.77 | MAPT (0.49) | ALDH1A1HPGDPOLB | |
| SCHEMBL23547262 | 0.77 | CYP17A1 (0.56) | ALDH1A1SMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4595840 | 0.75 | L3MBTL1 (0.48) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15388438 | 0.73 | HSD17B1 (0.40) | ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259469-A | DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY | EASTMAN KODAK COMPANY (US) | 1981-03-31 | — | — | US | disclosed |