Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349490 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTMAOBMAOAMTNR1A | |
| SCHEMBL11347391 | 0.82 | L3MBTL1 (0.35) | ALDH1A1MAPTMAOAKMT2ANPC1 | |
| SCHEMBL11180901 | 0.79 | MEN1 (0.40) | ALDH1A1MAPTHTTTDP1MAOB | |
| SCHEMBL11180716 | 0.79 | MAOA (0.39) | ALDH1A1HTTTDP1MAOBMAOA | |
| SCHEMBL11347085 | 0.78 | L3MBTL1 (0.35) | APPALDH1A1MAPTTDP1SMN1; SMN2 | |
| Dimethylamine SCHEMBL11347087 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTHTTTDP1KDM4E | |
| SCHEMBL3228582 | 0.70 | APP (0.82) | APPALDH1A1MAOBMAOADAO | |
| SCHEMBL18883700 | 0.69 | ALDH1A1 (0.49) | APPALDH1A1MAPTHTTTDP1 | |
| SCHEMBL418525 | 0.67 | ALDH1A1 (0.59) | APPALDH1A1MAPTMAOBMAOA | |
| SCHEMBL11351505 | 0.67 | HTR2C (0.36) | ALDH1A1TDP1MAOBMAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |