Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351610 | 0.83 | L3MBTL1 (0.45) | MEN1KMT2AMAOBALDH1A1MAPT | |
| SCHEMBL11178221 | 0.83 | L3MBTL1 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11352659 | 0.83 | CA2 (0.36) | IDO1SMN1; SMN2L3MBTL1LMNAHSP90AA1 | |
| SCHEMBL11347391 | 0.83 | L3MBTL1 (0.35) | KMT2AIDO1ALDH1A1MAPTMAOA | |
| SCHEMBL11174291 | 0.82 | NPC1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11351617 | 0.79 | RAB9A (0.41) | IDO1ALDH1A1SMN1; SMN2L3MBTL1HTT | |
| SCHEMBL11347085 | 0.79 | L3MBTL1 (0.35) | IDO1ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11180204 | 0.79 | ALDH1A1 (0.35) | MAOBIDO1ALDH1A1MAPTMAOA | |
| Dimethylamine SCHEMBL11347087 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11343239 | 0.76 | ANPEP (0.39) | IDO1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |