Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL819428 | 0.81 | SLC25A5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL813259 | 0.81 | MAPT (0.39) | — | |
| Hydrochloric Acid SCHEMBL2804147 | 0.80 | ACHE (0.35) | — | |
| Hydrochloric Acid SCHEMBL78567 | 0.80 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL5080418 | 0.79 | KEAP1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7050910 | 0.79 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL5080569 | 0.79 | — | — | |
| Bromide SCHEMBL5079505 | 0.79 | MAPT (0.39) | — | |
| Hydrochloric Acid SCHEMBL5079471 | 0.78 | EPHX2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5083580 | 0.78 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523416-B1 | Catalyst and process for preparing high molecular weight polyolefines | TARGOR GMBH (DE) | 1999-10-20 | — | — | EP | claimed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | claimed |
| US-5587501-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-24 | — | — | US | claimed |
| US-5539066-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | claimed |
| EP-0516019-B1 | Process for preparing syndiotactic polyolefins with large molecular weight distribution | HOECHST AG (DE) | 1995-12-27 | — | — | EP | claimed |
| US-5232993-A | Homo and copolymerization of propylene in two stages, in the presence of a catalyst having a transition metal component and an organoaluminum compound. | HOECHST AG (DE) | 1993-08-03 | — | — | US | claimed |
| EP-0513380-B2 | PROCESS FOR PRODUCING OLEFINIC POLYMER | IDEMITSU KOSAN CO (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-6713426-B1 | METHYL(PHENYL)METHYLENE)(9-FLUORENYL)(CYCLOPENTADIENYL) ZIRCONIUM DICHLORIDE OR THE (DIPHENYLMETHYLENE) COMPLEX; VERY HIGH MOLECULAR WEIGHT, NARROW MOLECULAR WEIGHT DISTRIBUTION; MOLDINGS ARE TRANSPARENT, FLEXIBLE, TEAR RESISTANT, AND GLOSSY | BASELL POLYOLEFINE GMBH (DE) | 2004-03-30 | — | — | US | disclosed |
| US-5731254-A | CATALYST | HOECHST (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0513380-B1 | PROCESS FOR PRODUCING OLEFINIC POLYMER | IDEMITSU KOSAN CO (JP) | 1997-10-01 | — | — | EP | disclosed |
| US-5663268-A | Syndiotactic propylene copolymers | HOECHST (DE) | 1997-09-02 | — | — | US | disclosed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5587501-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5369196-A | Production process of olefin based polymers | IDEMITSU KOSAN CO., LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5232993-A | Homo and copolymerization of propylene in two stages, in the presence of a catalyst having a transition metal component and an organoaluminum compound. | HOECHST AG (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0513380-A1 | PROCESS FOR PRODUCING OLEFINIC POLYMER | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |