Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | FABP3 | P05413 | 5/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11368610 | 0.91 | BBOX1 (0.52) | BBOX1CA1FABP3NFKB1 | |
| Propionic Acid SCHEMBL11380330 | 0.79 | CA2 (0.42) | BBOX1CA1FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL106656 | 0.78 | BBOX1 (0.58) | BBOX1CA1FABP3FFAR3HDAC3 | |
| SCHEMBL28873860 | 0.78 | CA1 (0.65) | BBOX1CA1FABP3FFAR3HDAC3 | |
| Adipic Acid SCHEMBL10431144 | 0.78 | BBOX1 (0.57) | BBOX1CA1FABP3FFAR3HDAC3 | |
| Adipic Acid SCHEMBL11364445 | 0.77 | LMNA (0.58) | FABP3NFKB1 | |
| Tetramethylammonium Ion SCHEMBL8438225 | 0.76 | BBOX1 (0.56) | BBOX1CA1FABP3FFAR3HDAC3 | |
| Sebacic Acid SCHEMBL5874500 | 0.76 | BBOX1 (0.56) | BBOX1CA1FABP3FFAR3HDAC3 | |
| Adipic Acid SCHEMBL8028995 | 0.76 | BBOX1 (0.56) | BBOX1CA1FABP3FFAR3HDAC3 | |
| Acetic Acid SCHEMBL11368283 | 0.75 | CA1 (0.53) | BBOX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255553-A | COMPRISING A COMPOUND HAVING AT LEAST TWO EPOXY GROUPS, A POLYESTER OR ACRYLIC RESIN, AND A QUARTERNARY AMMONIUM CARBOXYLATE AS CATALYST | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |