Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382507 | 0.89 | SETD7 (0.38) | OPRD1SETD7 | |
| SCHEMBL6450278 | 0.86 | ALDH1A1 (0.35) | OPRD1OPRK1MEN1ALDH1A1MAPT | |
| SCHEMBL4580935 | 0.76 | OPRM1 (0.44) | OPRD1OPRK1MEN1ALDH1A1MAPT | |
| SCHEMBL11382034 | 0.74 | OPRK1 (0.50) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11380464 | 0.73 | OPRK1 (0.49) | OPRD1OPRK1 | |
| SCHEMBL29342594 | 0.70 | POLB (0.47) | KMT2A | |
| SCHEMBL31072774 | 0.70 | POLB (0.47) | KMT2A | |
| SCHEMBL1969399 | 0.70 | LMNA (0.51) | OPRD1OPRK1SETD7MEN1ALDH1A1 | |
| SCHEMBL13477414 | 0.67 | PARP1 (0.47) | MAPTKMT2A | |
| SCHEMBL395978 | 0.66 | PIN1 (0.54) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |