Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384303 | 0.90 | ALPL (0.44) | ALPLALPGOPRD1OPRK1OPRM1 | |
| SCHEMBL11373711 | 0.88 | OPRD1 (0.48) | MAPK14OPRD1OPRK1OPRM1HTR7 | |
| SCHEMBL6449193 | 0.76 | OPRM1 (0.41) | MAPK14OPRD1OPRK1OPRM1GAA | |
| SCHEMBL11369771 | 0.71 | CYP2J2 (0.52) | OPRD1OPRK1OPRM1HTR7DRD2 | |
| SCHEMBL11379114 | 0.71 | OPRD1 (0.47) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL4257154 | 0.70 | SETD7 (0.56) | OPRD1OPRK1OPRM1SETD7ALDH1A1 | |
| SCHEMBL10459085 | 0.68 | ACHE (0.53) | OPRD1OPRM1GAAALDH1A1KMT2A | |
| SCHEMBL11036336 | 0.68 | SETD7 (0.53) | OPRD1OPRK1OPRM1SETD7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9365989 | 0.68 | ACHE (0.52) | OPRD1OPRM1GAAALDH1A1KMT2A | |
| SCHEMBL6452534 | 0.67 | SETD7 (0.41) | OPRD1OPRM1GAASETD7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |