Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.67 |
| ▸ | BACE1 | P56817 | 11/20 | 0.67 |
| ▸ | BCHE | P06276 | 9/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384082 | 0.86 | MEN1 (0.62) | ACHEBACE1BCHEHTR7MEN1 | |
| SCHEMBL11370258 | 0.82 | ACHE (0.61) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11381420 | 0.80 | HTR7 (0.58) | ACHEBACE1HTR7KMT2A | |
| SCHEMBL11371638 | 0.78 | ACHE (0.68) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4205093 | 0.76 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL14367985 | 0.75 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11372233 | 0.75 | BACE1 (0.65) | ACHEBACE1BCHEHTR7 | |
| SCHEMBL7695958 | 0.74 | HTR5A (0.77) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11371722 | 0.74 | ACHE (0.50) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11378628 | 0.74 | ACHE (0.52) | ACHEBACE1BCHEHTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |