Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 10/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384809 | 0.91 | GUSB (0.56) | GUSBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11374673 | 0.91 | GUSB (0.58) | GUSBKDM4EALDH1A1HPGDPDE5A | |
| SCHEMBL11375840 | 0.87 | ALDH1A1 (0.58) | GUSBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11374270 | 0.85 | ALDH1A1 (0.55) | GUSBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11383679 | 0.82 | PDE5A (0.66) | GUSBKDM4EALDH1A1HPGDPDE5A | |
| SCHEMBL11384695 | 0.82 | GUSB (0.71) | GUSBPDE5APDE10AMEN1MAPT | |
| SCHEMBL11380722 | 0.81 | PDE5A (0.59) | GUSBKDM4EALDH1A1HPGDPDE5A | |
| SCHEMBL11553644 | 0.81 | ALDH1A1 (0.53) | GUSBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11375259 | 0.81 | PDE5A (0.58) | GUSBKDM4EALDH1A1HPGDPDE5A | |
| SCHEMBL11554449 | 0.80 | GUSB (0.47) | GUSBPDE5APDE10AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |