Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272785 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPK1NPC1 | |
| SCHEMBL7698399 | 0.83 | THRB (0.45) | ALDH1A1HPGDKDM4EMAPK1NPC1 | |
| SCHEMBL27934756 | 0.82 | RAB9A (0.48) | RAD52ALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL17461905 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMAPK1NPC1 | |
| SCHEMBL13777821 | 0.81 | RAD52 (0.48) | RAD52ALDH1A1HPGDMAPK1NPC1 | |
| SCHEMBL13006148 | 0.80 | RAD52 (0.43) | RAD52ALDH1A1KDM4ETSHRTDP1 | |
| Trimethylammonium SCHEMBL9482623 | 0.80 | ALDH1A1 (0.58) | RAD52ALDH1A1HPGDMAPK1NPC1 | |
| SCHEMBL2387794 | 0.79 | NPC1 (0.57) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL86139 | 0.79 | ALDH1A1 (0.47) | RAD52ALDH1A1HPGDMAPK1NPC1 | |
| SCHEMBL8652676 | 0.79 | LMNA (0.45) | RAD52ALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284551-A | PROMOTERS FOR CURING AND POLYMERIZATION OF METHACRYLATES | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1981-08-18 | — | — | US | disclosed |