Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE6C | P51160 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382937 | 0.90 | PDE5A (0.44) | PDE5AKDM4EPDE2APDE9APDE4A | |
| SCHEMBL11381837 | 0.89 | PDE5A (0.53) | PDE5AKDM4EPDE2APDE9APDE4A | |
| SCHEMBL11381526 | 0.88 | NPSR1 (0.50) | ALDH1A1KDM4EGAAHPGDPDE4A | |
| SCHEMBL11377346 | 0.87 | NPSR1 (0.46) | PDE5AALDH1A1HTTMAPTMEN1 | |
| SCHEMBL11389001 | 0.85 | PKM (0.46) | PDE5AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL11381304 | 0.85 | PDE5A (0.48) | PDE5AALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL11381858 | 0.83 | ALDH1A1 (0.48) | PDE5AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11382440 | 0.81 | ALDH1A1 (0.50) | PDE5AALDH1A1HTTKDM4EHPGD | |
| SCHEMBL11380547 | 0.80 | MGLL (0.48) | ALDH1A1KDM4EHPGDPDE4AMAPT | |
| SCHEMBL11375670 | 0.80 | GUSB (0.56) | HTTKDM4EHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |