Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | PARG | Q86W56 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 4/20 | 0.37 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377346 | 0.90 | NPSR1 (0.46) | NPSR1LMNAHTTHIF1AMCOLN3 | |
| SCHEMBL11374918 | 0.90 | NPSR1 (0.42) | NPSR1LMNAPARGPDE5AALDH1A1 | |
| SCHEMBL11382937 | 0.88 | PDE5A (0.44) | PARGPDE5AABCC5 | |
| SCHEMBL11384755 | 0.86 | PDE5A (0.42) | PDE5AMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11384758 | 0.85 | LMNA (0.49) | NPSR1LMNAHTTHIF1AMCOLN3 | |
| SCHEMBL11559725 | 0.82 | TP53 (0.44) | PDE5AMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11381526 | 0.82 | NPSR1 (0.50) | NPSR1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL11390124 | 0.81 | PDE5A (0.41) | PDE5AMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11381968 | 0.80 | WDR5 (0.41) | NPSR1LMNAHTTHIF1AMCOLN3 | |
| SCHEMBL11382440 | 0.80 | ALDH1A1 (0.50) | NPSR1LMNAHTTHIF1AMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |