Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376235 | 0.90 | NPSR1 (0.44) | NPSR1HTTLMNAHIF1AMCOLN3 | |
| SCHEMBL11381968 | 0.90 | WDR5 (0.41) | NPSR1HTTLMNAHIF1AMCOLN3 | |
| SCHEMBL11382440 | 0.90 | ALDH1A1 (0.50) | NPSR1HTTLMNAHIF1AMCOLN3 | |
| SCHEMBL11381526 | 0.88 | NPSR1 (0.50) | NPSR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11384758 | 0.88 | LMNA (0.49) | NPSR1HTTLMNAHIF1AMCOLN3 | |
| SCHEMBL11389378 | 0.87 | PDE5A (0.46) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11389001 | 0.85 | PKM (0.46) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL11381304 | 0.81 | PDE5A (0.48) | LMNAALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11375670 | 0.80 | GUSB (0.56) | NPSR1HTTLMNAMAPTPOLB | |
| SCHEMBL11380547 | 0.80 | MGLL (0.48) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |