Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SQLE | Q14534 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407941 | 0.83 | MME (0.36) | SIGMAR1CNR2CTNNB1MMEACE | |
| SCHEMBL7018449 | 0.79 | SIGMAR1 (0.53) | SIGMAR1CTNNB1CYP2D6LMNAADRA2A | |
| SCHEMBL11399752 | 0.78 | SIGMAR1 (0.39) | SIGMAR1CTNNB1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL9727662 | 0.72 | CTNNB1 (0.45) | SIGMAR1CTNNB1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL9631575 | 0.72 | CTNNB1 (0.45) | SIGMAR1CTNNB1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25660784 | 0.72 | CTNNB1 (0.45) | SIGMAR1CTNNB1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL9633247 | 0.71 | CYP2D6 (0.65) | SIGMAR1CYP2D6LMNAADRA2ASLC6A2 | |
| SCHEMBL9633240 | 0.71 | CYP2D6 (0.65) | SIGMAR1CYP2D6LMNAADRA2ASLC6A2 | |
| SCHEMBL7058293 | 0.68 | KMT2A (0.43) | SIGMAR1CNR2NR3C1PGRNR3C2 | |
| SCHEMBL16174128 | 0.66 | NR3C1 (0.54) | SIGMAR1NR3C1PGRNR3C2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024587-A1 | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ AG (CH) | 1981-03-11 | — | — | EP | claimed |
| EP-0024587-A1 | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ AG (CH) | 1981-03-11 | — | — | EP | disclosed |