Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143247 | 0.81 | SIRT1 (0.47) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL11478885 | 0.79 | CYP2C9 (0.59) | MMP2MMP9MMP12AGBL2CYP2C9 | |
| SCHEMBL11427398 | 0.77 | ALDH1A1 (0.46) | MMP2MMP9MMP12AGBL2CYP2C9 | |
| SCHEMBL11430852 | 0.76 | MMP2 (0.60) | MMP2MMP9MMP12ALDH1A1MEN1 | |
| SCHEMBL11400370 | 0.75 | AKR1B1 (0.46) | MMP2MMP9MMP12AGBL2CYP2C9 | |
| SCHEMBL11554666 | 0.74 | MMP2 (0.49) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| Oxirane SCHEMBL11442758 | 0.74 | SIRT1 (0.41) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL11552435 | 0.74 | SLC6A2 (0.44) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL11452309 | 0.72 | MMP2 (0.41) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL11398613 | 0.71 | MMP2 (0.44) | MMP2MMP9MMP12AGBL2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |