Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410674 | 0.81 | MAPT (0.42) | MAPTALDH1A1CYP3A4TSHRPTGS2 | |
| SCHEMBL11507747 | 0.69 | ALDH1A1 (0.56) | MAPTALDH1A1CYP3A4TSHRTP53 | |
| SCHEMBL10879274 | 0.69 | RAB9A (0.47) | MAPTALDH1A1CYP3A4TSHRDDB1 | |
| SCHEMBL8240202 | 0.68 | MAPT (0.41) | MAPTALDH1A1CYP3A4TSHRPTGS2 | |
| SCHEMBL14227971 | 0.67 | ALDH1A1 (0.53) | MAPTALDH1A1CYP3A4TSHRTP53 | |
| SCHEMBL5761130 | 0.67 | GAA (0.52) | MAPTALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL31006317 | 0.65 | HTR6 (0.61) | MAPTALDH1A1LMNA | |
| SCHEMBL11369193 | 0.64 | MAPT (0.97) | MAPTALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL3105222 | 0.64 | MMP2 (0.65) | ALDH1A1SMN1; SMN2GAAACHEPOLB | |
| SCHEMBL22623715 | 0.64 | CRBN (0.72) | MAPTALDH1A1TSHRDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013995-A1 | Process for the preparation of acetylenic macrocyclic ketones | FIRMENICH SA (CH) | 1980-08-06 | — | — | EP | disclosed |