Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881536 | 0.81 | HPGD (0.57) | HPGDHDAC1ALDH1A1RAB9ATSHR | |
| SCHEMBL5179083 | 0.80 | HPGD (1.00) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL3383085 | 0.80 | HPGD (1.00) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL2415331 | 0.78 | HPGD (0.96) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL11092658 | 0.78 | LMNA (0.47) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL5179130 | 0.75 | HPGD (0.90) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL27643228 | 0.72 | HPGD (0.63) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| SCHEMBL759462 | 0.72 | ALDH1A1 (0.84) | HPGDHDAC1ALDH1A1LMNAPOLB | |
| Bromide SCHEMBL11446589 | 0.71 | MAPT (0.60) | HDAC1LMNATSHRMAPK1HDAC3 | |
| SCHEMBL14088974 | 0.71 | KDM4E (0.73) | HPGDHDAC1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |