Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | NPC1 | O15118 | 2/20 | 0.84 |
| ▸ | RAB9A | P51151 | 2/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | HPGD | P15428 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.60 |
| ▸ | WNT3A | P56704 | 4/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1373347 | 0.98 | ALDH1A1 (0.81) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL2216212 | 0.92 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL5179130 | 0.89 | HPGD (0.90) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL2415331 | 0.89 | HPGD (0.96) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL5179083 | 0.87 | HPGD (1.00) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3383085 | 0.87 | HPGD (1.00) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL9466891 | 0.85 | HPGD (0.63) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL15979661 | 0.85 | ALDH1A1 (0.78) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL22721189 | 0.83 | ALDH1A1 (0.83) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL18755474 | 0.82 | ALDH1A1 (0.81) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | GUIZHOU UNIVERSITY (CN) | 2024-01-30 | — | — | US | claimed |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | GUIZHOU UNIVERSITY (CN) | 2022-06-09 | — | — | US | claimed |
| WO-2020228170-A1 | CATALYST-FREE SYNTHESIS METHOD FOR LACTAM DERIVATIVE | 贵州大学 | 2020-11-19 | — | — | WO | claimed |
| CN-109942473-B | Method for synthesizing lactam derivative without catalyst | 贵州大学 | 2020-09-15 | — | — | CN | claimed |
| CN-109942473-A | A kind of method of catalyst-free synthesis lactam derivatives | 贵州大学 | 2019-06-28 | — | — | CN | claimed |
| US-7691889-B2 | Antimycobacterial compounds | LUPIN LIMITED (IN) | 2010-04-06 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-20050192275-A1 | Novel antimycobacterial compounds | LUPIN LIMITED (IN) | 2005-09-01 | — | — | US | claimed |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | AVENTIS PHARMA S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | claimed |
| CN-115894434-B | Preparation method of 4-piperazinyl benzothiophene hydrochloride | 山东厚德精诚药业有限公司 | 2024-10-08 | — | — | CN | disclosed |
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | GUIZHOU UNIVERSITY (CN) | 2024-01-30 | — | — | US | disclosed |
| CN-115894434-A | Preparation method of 4-piperazinyl benzothiophene hydrochloride | 山东厚德精诚药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | GUIZHOU UNIVERSITY (CN) | 2022-06-09 | — | — | US | disclosed |
| US-11269251-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-03-08 | — | — | US | disclosed |
| US-4096155-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4075228-A | INTERMEDIATES FOR ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-4055644-A | CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3931176-A | CNS DEPRESSANT | SANDOZ INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884628-B2 | Method for synthesizing lactam derivatives without use of catalyst | COASY, SI, NAAA | ALDH1A1 1960/4885LMNA 3590/4885MEN1 1464/4885 |
| US-20220177429-A1 | METHOD FOR SYNTHESIZING LACTAM DERIVATIVES WITHOUT USE OF CATALYST | COASY, SI, NAAA | ALDH1A1 1960/4885LMNA 3590/4885MEN1 1464/4885 |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | HEXD, CDK5, CHUK | ALDH1A1 454/4885LMNA 2840/4885MEN1 1864/4885 |
| US-20050192275-A1 | Novel antimycobacterial compounds | MDH1, IMMT, MLYCD | ALDH1A1 1995/4885LMNA 3191/4885MEN1 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.