Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.43 |
| ▸ | MMP13 | P45452 | 4/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24291657 | 0.83 | ALDH1A1 (0.43) | LDHAL3MBTL1ALDH1A1BMP1TDP1 | |
| SCHEMBL5494081 | 0.81 | LDHA (0.43) | LDHAL3MBTL1ALDH1A1BMP1PPARG | |
| SCHEMBL11400130 | 0.81 | LDHA (0.43) | LDHAL3MBTL1ALDH1A1BMP1PPARG | |
| SCHEMBL11148899 | 0.81 | LDHA (0.43) | LDHAL3MBTL1ALDH1A1BMP1PPARG | |
| SCHEMBL11579749 | 0.81 | LDHA (0.43) | LDHAL3MBTL1ALDH1A1BMP1PPARG | |
| SCHEMBL10519344 | 0.81 | LDHA (0.43) | LDHAL3MBTL1ALDH1A1BMP1PPARG | |
| SCHEMBL30552447 | 0.79 | PDE4B (0.48) | L3MBTL1ALDH1A1LMNAHSD17B10PPARG | |
| SCHEMBL16991845 | 0.79 | ALDH1A1 (0.49) | LDHAL3MBTL1ALDH1A1LMNAPOLB | |
| SCHEMBL25609121 | 0.79 | ALDH1A1 (0.41) | LDHAL3MBTL1ALDH1A1PPARGPPARA | |
| SCHEMBL21741216 | 0.78 | L3MBTL1 (0.41) | LDHAL3MBTL1ALDH1A1TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624900-A | HIGH BINDING ACTIVITY FOR HUMAN INTERLEUKIN-1; TREATING RHEUMATOID ARTHRITIS | KURARAY CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0474141-B1 | Peptide or its salts | KURARAY CO (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0474141-A1 | Peptide or its salts | KURARAY CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |