Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267916 | 0.84 | CAPN1 (0.48) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL11270328 | 0.79 | POLB (0.47) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL11256499 | 0.79 | NPSR1 (0.49) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL11263507 | 0.79 | LMNA (0.47) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL8726366 | 0.79 | PLA2G10 (0.56) | ALOX15L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL11264004 | 0.78 | MMP1 (0.40) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL11257403 | 0.78 | RAB9A (0.53) | ALOX15L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL11265232 | 0.77 | PLA2G10 (0.48) | ALOX15L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL11266748 | 0.77 | L3MBTL1 (0.42) | ALOX15L3MBTL1POLBKDM4AUSP2 | |
| SCHEMBL11263373 | 0.76 | KMT2A (0.52) | ALOX15L3MBTL1POLBKDM4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |