Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084830 | 0.87 | MAPT (0.46) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL29111785 | 0.83 | NPC1 (0.65) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL11080583 | 0.79 | KDM4E (0.49) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL11399779 | 0.77 | RAB9A (0.44) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL29111861 | 0.77 | RAB9A (0.52) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL29111820 | 0.76 | PTGS2 (0.52) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL30701191 | 0.75 | NPC1 (0.73) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4022996 | 0.75 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL5829385 | 0.73 | SRC (0.54) | KMT2AMEN1HTTALDH1A1NPC1 | |
| SCHEMBL11074786 | 0.73 | KDM4E (0.52) | KMT2AALDH1A1RAB9ALMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |