Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818244 | 0.83 | TSHR (0.43) | EGFRERBB2ALDH1A1LMNAPOLB | |
| SCHEMBL616398 | 0.83 | HPGD (0.47) | ALDH1A1LMNAPOLBKMT2ANPC1 | |
| SCHEMBL1818475 | 0.76 | POLB (0.46) | EGFRERBB2LMNAPOLBKMT2A | |
| SCHEMBL27857181 | 0.76 | HDAC1 (0.49) | EGFRERBB2ALDH1A1LMNAPOLB | |
| SCHEMBL11789928 | 0.76 | LMNA (0.47) | EGFRERBB2ALDH1A1LMNAPOLB | |
| SCHEMBL1139982 | 0.75 | MLYCD (0.54) | LMNAPOLBSMN1; SMN2KMT2ACHRNB2 | |
| SCHEMBL7872104 | 0.75 | CHRNB2 (0.46) | EGFRERBB2ALDH1A1LMNAPOLB | |
| SCHEMBL4425563 | 0.74 | TSHR (0.46) | ALDH1A1POLBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL28711269 | 0.73 | KMT2A (0.42) | EGFRERBB2ALDH1A1POLBKMT2A | |
| SCHEMBL28711268 | 0.73 | KMT2A (0.42) | EGFRERBB2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55057566-A | — | — | None | — | — | JP | disclosed |
| JP-S5557566-A | N-METHYL-8-CHLORO-3,4-DIHYDRO-2-QUINOLINONE, ITS PREPARATION, AND GERMICIDE CONTAINING THE SAME | KUMIAI CHEM IND CO LTD | 1980-04-28 | — | — | JP | disclosed |