Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205813 | 0.91 | LMNA (0.44) | LMNASMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL2106150 | 0.86 | TSHR (0.41) | ALDH1A1HTTNPSR1 | |
| SCHEMBL6069562 | 0.79 | CHRNB2 (0.41) | ALDH1A1 | |
| SCHEMBL28217399 | 0.78 | ESR1 (0.56) | LMNAALDH1A1IDO1TDO2CNR2 | |
| SCHEMBL9180217 | 0.78 | ALDH1A1 (0.54) | LMNASMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL5052368 | 0.78 | ALDH1A1 (0.74) | LMNASMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL7493934 | 0.78 | IDO1 (0.48) | LMNAALDH1A1CYP19A1IDO1TDO2 | |
| SCHEMBL3061827 | 0.75 | DPP4 (0.48) | LMNASMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL11408107 | 0.75 | IDO1 (0.36) | IDO1TDO2 | |
| Fluorobenzene SCHEMBL1444304 | 0.74 | ALDH1A1 (0.69) | LMNASMN1; SMN2HPGDALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | claimed |
| WO-2007140058-A1 | PHOTOCHROMIC MATERIALS COMPRISING METALLOCENYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | WO | disclosed |