Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719325 | 0.91 | TSHR (0.44) | IDO1TDO2TSHRHIF1ASLC6A2 | |
| SCHEMBL2106150 | 0.86 | TSHR (0.41) | TSHRL3MBTL1ALDH1A1CYP2D6 | |
| SCHEMBL6069562 | 0.79 | CHRNB2 (0.41) | TSHRTDP1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL9189085 | 0.78 | IDO1 (0.48) | IDO1TDO2TSHRHIF1ASLC6A2 | |
| SCHEMBL5164828 | 0.78 | L3MBTL1 (0.56) | IDO1TDO2TSHRSLC6A2SLC6A4 | |
| SCHEMBL5324736 | 0.78 | LMNA (0.50) | IDO1TDO2SLC6A4SLC6A3LMNA | |
| SCHEMBL28217399 | 0.78 | ESR1 (0.56) | IDO1TDO2TDP1LMNACNR1 | |
| Hydrochloric Acid SCHEMBL27736240 | 0.77 | L3MBTL1 (0.54) | IDO1TDO2TSHRCYP2C19TDP1 | |
| SCHEMBL588409 | 0.75 | IDO1 (0.59) | IDO1TDO2TSHRHIF1ASLC6A2 | |
| SCHEMBL587761 | 0.75 | IDO1 (0.59) | IDO1TDO2TSHRHIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | claimed |