Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21526675 | 0.87 | CYP3A4 (0.36) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL21526667 | 0.83 | THRB (0.33) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7765472 | 0.82 | KMT2A (0.36) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL21526693 | 0.75 | ALDH1A1 (0.33) | CYP3A4ALDH1A1LMNAMEN1MAPT | |
| SCHEMBL18685990 | 0.75 | — | — | |
| SCHEMBL4216034 | 0.74 | HSD11B1 (0.38) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2160193 | 0.74 | HSD11B1 (0.41) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11520353 | 0.73 | GAA (0.36) | ALDH1A1HSD17B10TSHRHSD11B1KDM4E | |
| SCHEMBL8954748 | 0.72 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL5284629 | 0.69 | ALDH1A1 (0.39) | CYP3A4ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199576-A | DERIVATIVES OF SALICYCLIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-04-22 | — | — | US | disclosed |