Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439331 | 0.91 | CASP6 (0.50) | APEX1KAT6AHSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL11427680 | 0.87 | CASP6 (0.59) | APEX1KAT6AHSD17B10SMN1; SMN2NT5E | |
| SCHEMBL10908211 | 0.85 | MEN1 (0.53) | APEX1HSD17B10NT5ETRPV1CASP6 | |
| SCHEMBL11337363 | 0.85 | TIMP3 (0.61) | APEX1HSD17B10TRPV1ALDH1A1MEN1 | |
| SCHEMBL11763835 | 0.85 | APEX1 (0.53) | APEX1KAT6AHSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL11433027 | 0.83 | KAT6A (0.46) | KAT6AHSD17B10SMN1; SMN2NPSR1CASP6 | |
| SCHEMBL11431303 | 0.83 | RAB9A (0.54) | APEX1SMN1; SMN2TRPV1CTDSP1ALDH1A1 | |
| SCHEMBL11426058 | 0.82 | CASP6 (0.43) | APEX1HSD17B10NT5ETRPV1CASP6 | |
| SCHEMBL11426646 | 0.82 | CASP6 (0.43) | APEX1HSD17B10NT5ETRPV1CASP6 | |
| SCHEMBL11434078 | 0.82 | CASP6 (0.50) | APEX1KAT6AHSD17B10SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |