Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426265 | 0.90 | CASP6 (0.65) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11426066 | 0.87 | APEX1 (0.50) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11350067 | 0.87 | TIMP3 (0.57) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL10905209 | 0.87 | ENPP2 (0.51) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11426058 | 0.85 | CASP6 (0.43) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11426646 | 0.85 | CASP6 (0.43) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11436268 | 0.84 | MAPT (0.57) | APEX1TRPV1ENPP2CA1CA2 | |
| SCHEMBL11425014 | 0.81 | CASP6 (0.57) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL10909117 | 0.81 | MEN1 (0.46) | CASP6CTDSP1APEX1NT5ETRPV1 | |
| SCHEMBL11339174 | 0.81 | HPSE (0.46) | APEX1TRPV1ENPP2NSD2TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |