Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 4/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439331 | 0.92 | CASP6 (0.50) | APEX1CASP6CTDSP1HSD17B10SMN1; SMN2 | |
| SCHEMBL11434078 | 0.92 | CASP6 (0.50) | APEX1CASP6CTDSP1HSD17B10SMN1; SMN2 | |
| SCHEMBL11597730 | 0.89 | CASP6 (0.56) | APEX1CASP6CTDSP1HSD17B10NSD2 | |
| SCHEMBL11763828 | 0.87 | FGF1 (0.55) | APEX1HSD17B10SMN1; SMN2NPSR1KAT6A | |
| SCHEMBL17115743 | 0.86 | APEX1 (0.70) | APEX1CASP6CTDSP1HSD17B10NSD2 | |
| SCHEMBL11426066 | 0.85 | APEX1 (0.50) | APEX1CASP6CTDSP1HSD17B10SMN1; SMN2 | |
| SCHEMBL11433757 | 0.85 | HSD17B10 (0.50) | APEX1CASP6CTDSP1HSD17B10SMN1; SMN2 | |
| SCHEMBL11761158 | 0.84 | TIMP3 (0.61) | APEX1CASP6CTDSP1HSD17B10NSD2 | |
| SCHEMBL5567709 | 0.84 | APEX1 (0.76) | APEX1CASP6CTDSP1HSD17B10SMN1; SMN2 | |
| SCHEMBL6560617 | 0.83 | CASP6 (0.77) | APEX1CASP6CTDSP1HSD17B10NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027038-A | NAPHTHALENEDISULFONIC ACID UREIDES | AMERICAN CYANAMID COMPANY (US) | 1977-05-31 | — | — | US | disclosed |