Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585105 | 0.73 | PDE10A (0.47) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28608866 | 0.72 | PDE10A (0.46) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL14582925 | 0.67 | PDE10A (0.44) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL7048629 | 0.67 | NCF1 (0.55) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL21017139 | 0.66 | ALDH1A1 (0.41) | RAB9ANPC1SMN1; SMN2PDE10AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28590788 | 0.66 | NCF1 (0.53) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL6034068 | 0.64 | HTT (0.50) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL5435508 | 0.64 | RAB9A (0.49) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL989154 | 0.63 | PDE10A (0.62) | KDM4EMAPTGAAPDE10AALDH1A1 | |
| SCHEMBL9837446 | 0.62 | KDM4E (0.39) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |