Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456891 | 0.83 | MEN1 (0.42) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11437822 | 0.83 | MEN1 (0.42) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11436717 | 0.79 | MEN1 (0.52) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11334220 | 0.79 | MEN1 (0.44) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11450497 | 0.77 | MAPK1 (0.40) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11434873 | 0.75 | CHRM2 (0.42) | MEN1KMT2ACHRM2CHRM3OPRM1 | |
| SCHEMBL11443811 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11465431 | 0.72 | HPGD (0.39) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11447020 | 0.70 | OPRD1 (0.42) | MEN1KMT2ASIGMAR1OPRM1OPRD1 | |
| SCHEMBL11446906 | 0.70 | SIGMAR1 (0.39) | MEN1KMT2ASIGMAR1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |