Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260624 | 0.90 | KDM4E (0.59) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL9845445 | 0.86 | MEN1 (0.51) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL18569422 | 0.83 | KDM4E (0.72) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL11456891 | 0.82 | MEN1 (0.42) | MEN1KMT2AOPRM1SIGMAR1CHRM3 | |
| SCHEMBL11437822 | 0.82 | MEN1 (0.42) | MEN1KMT2AOPRM1SIGMAR1CHRM3 | |
| SCHEMBL11334220 | 0.81 | MEN1 (0.44) | MEN1KMT2AOPRM1SIGMAR1CHRM3 | |
| SCHEMBL11434689 | 0.79 | MEN1 (0.40) | MEN1KMT2AOPRM1SIGMAR1CHRM3 | |
| SCHEMBL9346956 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12952656 | 0.75 | HRH3 (0.45) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL18609525 | 0.74 | OPRM1 (0.85) | OPRM1SIGMAR1CHRM3KCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |