Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446905 | 0.78 | MEN1 (0.38) | CHRM2CHRM3OPRD1OPRM1OPRK1 | |
| SCHEMBL11434686 | 0.77 | OPRM1 (0.43) | CHRM3CHRM1OPRD1OPRM1OPRK1 | |
| SCHEMBL11434873 | 0.77 | CHRM2 (0.42) | CHRM2CHRM3CHRM5CHRM1OPRD1 | |
| SCHEMBL11447936 | 0.76 | SIGMAR1 (0.41) | CHRM2CHRM3OPRD1OPRM1OPRK1 | |
| SCHEMBL11454799 | 0.75 | OPRM1 (0.41) | CHRM2CHRM3CHRM1OPRD1OPRM1 | |
| SCHEMBL11331578 | 0.71 | ALDH1A1 (0.40) | CHRM2CHRM3OPRD1OPRM1OPRK1 | |
| SCHEMBL11436426 | 0.71 | MLYCD (0.42) | CHRM2CHRM3CHRM5CHRM1OPRD1 | |
| SCHEMBL11436432 | 0.71 | ALDH1A1 (0.36) | CHRM2CHRM3OPRD1MEN1KMT2A | |
| SCHEMBL11436258 | 0.71 | OPRM1 (0.41) | CHRM3CHRM1OPRD1OPRM1OPRK1 | |
| SCHEMBL11350690 | 0.69 | L3MBTL1 (0.41) | CHRM2CHRM3CHRM1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |