SCHEMBL399595

SCHEMBL399595

C=C(C(=O)O)C1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.41
POLB P06746 1/20 0.41
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
SRD5A2 P31213 1/20 0.36
HSD17B10 Q99714 1/20 0.35
SLC6A1 P30531 2/20 0.34
SLC6A11 P48066 1/20 0.34
LMNA P02545 1/20 0.34
SLC6A13 Q9NSD5 1/20 0.34
HPGD P15428 1/20 0.33
HSD11B1 P28845 1/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
EPHX1 P07099 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599659 0.97 CES2 (0.50) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL221713 0.97 CES2 (0.50) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL642121 0.97 CES2 (0.50) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL1122749 0.97 CES2 (0.50) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL791540 0.97 CES2 (0.50) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL4962068 0.94
SCHEMBL29207086 0.93 CES2 (0.46) CES2CES1SMN1; SMN2POLBHDAC8
SCHEMBL26124 0.88
SCHEMBL20838334 0.88 SMN1; SMN2 (0.39) CES2CES1SMN1; SMN2POLBTSHR
Acrylic Acid SCHEMBL1715031 0.87 LMNA (0.42) CES2CES1SMN1; SMN2POLBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 813 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-3642276-B1 POLYVINYL CHLORIDE COMPOSITIONS CONTAINING IMPACT MODIFIERS AND CALCIUM CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-25 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-3994219-B1 A COATING COMPOSITION, ITS PREPARATION METHOD AND USE THEREOF BASF COATINGS GMBH (DE) 2025-10-08 EP claimed
EP-4529621-A1 UV/HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 EP claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-3847220-B1 UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS BASF SE (DE) 2025-03-05 EP claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-2173791-B1 WATER-BASED DISPERSIONS OF HIGHLY-BRANCHED POLYMERS BASF CORP (US) 2014-06-18 EP claimed
EP-2231777-B1 CHEMICAL AND IMPACT RESISTANT THERMOPLASTIC RESIN COMPOSITION HAVING IMPROVED EXTRUDABILITY. CHEIL IND INC (KR) 2014-04-30 EP claimed
EP-2456792-B1 PROCESS FOR THE PRODUCTION OF CONDENSATION POLYMERS VIA IN-REACTOR CHAIN EXTENSION AND PRODUCTS THEREOF BASF CORP (US) 2014-03-12 EP claimed
US-8394522-B2 Robust metal film encapsulation INFINITE POWER SOLUTIONS, INC. (US) 2013-03-12 US claimed
EP-2272120-A2 ROBUST METAL FILM ENCAPSULATION Infinite Power Solutions, Inc. (US) 2011-01-12 EP claimed
WO-2009134689-A2 ROBUST METAL FILM ENCAPSULATION INFINITE POWER SOLUTIONS, INC. (US) 2009-11-05 WO claimed
US-20080261107-A1 ROBUST METAL FILM ENCAPSULATION SAPURAST RESEARCH LLC 2008-10-23 US claimed
EP-1203029-B1 PROCESS FOR THE CONTINUOUS PRODUCTION OF GEL FREE POLYMERS, AND POWDER AND LIQUID COATING APPLICATIONS CONTAINING GEL FREE POLYMERS JOHNSON POLYMER INC (US) 2004-11-10 EP claimed
EP-0590573-B1 Resin for plastic lens HITACHI CHEMICAL CO LTD (JP) 1998-01-07 EP claimed
EP-0067308-B1 NEUTRALIZING LAYER FOR COLOR TRANSFER ASSEMBLAGES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-03-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA CES2 2101/4885CES1 1849/4885SMN1; SMN2 4286/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L CES2 1235/4885CES1 1618/4885SMN1; SMN2 4624/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA CES2 1694/4885CES1 621/4885SMN1; SMN2 4766/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA CES2 1474/4885CES1 2055/4885SMN1; SMN2 4239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.