Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | PDE8A | O60658 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892209 | 0.87 | MAPT (0.52) | CNR1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL9501879 | 0.76 | NPC1 (0.56) | CNR1CNR2SMN1; SMN2KDM4EMAPT | |
| SCHEMBL27961959 | 0.75 | PLK1 (0.65) | PREPPOLBHDAC2HDAC6MMP3 | |
| SCHEMBL11105640 | 0.74 | KDM4E (0.60) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL11435882 | 0.73 | PARP1 (0.51) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL11556569 | 0.73 | KDM4E (0.40) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL11195781 | 0.73 | MAPT (0.55) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL1250218 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2662445 | 0.72 | ALPL (0.61) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL153149 | 0.72 | LMNA (0.58) | SMN1; SMN2NPC1RAB9AKMT2AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |