Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | AQP4 | P55087 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151398 | 0.84 | NPC1 (0.50) | KCNK3RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9756889 | 0.83 | LMNA (0.42) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL12892192 | 0.82 | KDM4E (0.46) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL13715916 | 0.81 | GAA (0.55) | LMNAKCNK3RAB9ATP53L3MBTL1 | |
| SCHEMBL4552789 | 0.80 | NPC1 (0.47) | KCNK3RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL13876946 | 0.79 | ALPL (0.40) | LMNARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL146921 | 0.78 | ALPL (0.60) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL13715634 | 0.78 | RAB9A (0.56) | LMNARAB9ANPC1TP53MEN1 | |
| SCHEMBL15326541 | 0.77 | MEN1 (0.55) | KCNK3RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5251977 | 0.77 | NPC1 (0.38) | RAB9ANPC1SMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773625-B1 | 5-PHENYL SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYL CARBOXYLIC ACID AMIDES AND USE OF SAME AS HERBICIDES | BAYER IP GMBH (DE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2016054806-A1 | SUBSTITTUED PYRIDINE INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-04-14 | — | — | WO | disclosed |
| US-9259001-B2 | 5-phenyl-substituted N-(tetrazol-5-yl) aryl carboxylic acid amides and N-(triazol-5-yl) aryl carboxylic acid amides, and use thereof as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| US-9169219-B2 | Herbicidally active 4-nitro-substituted N-(tetrazol-5-yl)-, N-(triazol-5-yl)-, and N-(1,3,4-0XADIAZOL-2-yl)aryl carboxylic acid amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| EP-2773626-B1 | HERBICIDALLY ACTIVE OXIME-ETHER-SUBSTITUTED BENZOYLAMIDES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-9035067-B2 | N-(1,2,5-Oxadiazol-3-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)bicycloarylcarboxamides and their use as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2739611-B1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYL CARBOXAMIDES AND THEIR USE AS HEBICIDES | BAYER IP GMBH (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-8957096-B2 | Herbicidally active oxime-ether-substituted benzoylamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-02-17 | — | — | US | disclosed |
| US-20150031537-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| EP-2686315-B1 | N-(1,2,5-OXADIAZOL-3-YL)-, N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)BICYCLOARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES | BAYER IP GMBH (DE) | 2015-01-14 | — | — | EP | disclosed |
| EP-2589598-A1 | 5-phenyl substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)aryl carboxylic acid amides and use of same as herbicides | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| WO-2013017559-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012123409-A1 | N-(1,2,5-OXADIAZOL-3-YL)-, N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)BICYCLOARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-20 | — | — | WO | disclosed |
| US-20120058892-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2012028579-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-20090203215-A1 | METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD | FUJIFILM CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203215-A1 | METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD | FUJIFILM CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-0053789-B1 | 2-PYRIDINECARBOXAMIDE DERIVATIVE, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITION, USEFUL AS AN ANTI-ALLERGIC AGENT | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4404214-A | 2-Pyridinecarboxamide derivatives compositions containing same and method of using same | TANABE SEIYAKU CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0053789-A1 | 2-Pyridinecarboxamide derivative, process for preparing same and pharmaceutical composition, useful as an anti-allergic agent | Tanabe Seiyaku Co., Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058892-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES | ZYX, NAT1, CYCS | LMNA 1711/4885HIF1A 2663/4885ROCK2 2333/4885 |
| US-20150031537-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | AADAC, NAT1, AOX1 | LMNA 3227/4885HIF1A 3058/4885ROCK2 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.