Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557699 | 0.87 | TERT (0.40) | KDM4EALDH1A1POLBALPLMEN1 | |
| SCHEMBL11560143 | 0.85 | MAPT (0.40) | KDM4EPOLBALPLSMN1; SMN2MEN1 | |
| SCHEMBL11559491 | 0.84 | KDR (0.51) | KDM4EALDH1A1POLBLMNAALPL | |
| SCHEMBL11560867 | 0.84 | KLKB1 (0.50) | KDM4EPOLBALPLSMN1; SMN2KMT2A | |
| SCHEMBL11559144 | 0.84 | HSPD1 (0.40) | KDM4EALDH1A1POLBALPLSMN1; SMN2 | |
| SCHEMBL12310841 | 0.84 | MMP2 (0.45) | KDM4EALDH1A1POLBALPLSMN1; SMN2 | |
| SCHEMBL11559540 | 0.82 | ERN1 (0.38) | KDM4EPOLBALPLMEN1KMT2A | |
| SCHEMBL11562445 | 0.81 | RAB9A (0.45) | ALDH1A1LMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL11559525 | 0.81 | CXCR2 (0.39) | KDM4EPOLBLMNAALPLMEN1 | |
| SCHEMBL11562864 | 0.81 | KLKB1 (0.53) | KDM4EPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |