Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ATF4 | P18848 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105460 | 0.91 | ATF4 (0.54) | ATF4MAPTRAB9APOLBHPGD | |
| SCHEMBL11377919 | 0.86 | LMNA (0.56) | LMNANR4A2SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL9362390 | 0.85 | ATF4 (0.50) | ATF4MAPTRAB9APOLBHPGD | |
| SCHEMBL11462481 | 0.84 | LMNA (0.55) | LMNANR4A2MAOAMAOBATF4 | |
| SCHEMBL2117441 | 0.82 | ALOX15 (0.50) | MAPTPOLBHPGDSMN1; SMN2MEN1 | |
| SCHEMBL11460802 | 0.79 | NPSR1 (0.57) | LMNAMAPTPOLBNPSR1PTGS2 | |
| Hydrochloric Acid SCHEMBL8698847 | 0.78 | PPARG (0.50) | RAB9ANPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2717252 | 0.78 | RXRA (0.53) | LMNAMAPTRAB9APOLBNPSR1 | |
| SCHEMBL7664334 | 0.78 | ADAMTS5 (0.52) | NR4A2RAB9APOLBMEN1KMT2A | |
| SCHEMBL11440981 | 0.77 | MAPT (0.60) | LMNAATF4MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182902-A | P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
| US-4153803-A | Cholesterol-lowering phenoxyalkanoic acid esters | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-05-08 | — | — | US | disclosed |
| US-4115393-A | Pyridyl alkyl esters of substituted phenoxy alkanoic acids having the ability to reduce the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1978-09-19 | — | — | US | disclosed |