Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469411 | 0.82 | ALDH1A1 (0.58) | MTNR1AMTNR1BCTNNB1WNT3ABCHE | |
| SCHEMBL10368997 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL11353867 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL5218968 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL5405021 | 0.73 | MTNR1A (0.52) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL5751450 | 0.73 | CTNNB1 (0.52) | MTNR1ACTNNB1WNT3AKDM4ERAB9A | |
| SCHEMBL11467578 | 0.73 | KDM4E (0.44) | MTNR1ACTNNB1WNT3AKDM4ERAB9A | |
| SCHEMBL16965115 | 0.71 | RAB9A (0.60) | BCHERAB9A | |
| SCHEMBL11358917 | 0.71 | MTNR1A (0.59) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E | |
| SCHEMBL13534215 | 0.70 | MTNR1A (0.59) | MTNR1AMTNR1BCTNNB1WNT3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234598-A | INSECTICIDE, MITICIDE | HOFFMANN-LA ROCHE INC. (US) | 1980-11-18 | — | — | US | claimed |
| US-4234598-A | INSECTICIDE, MITICIDE | HOFFMANN-LA ROCHE INC. (US) | 1980-11-18 | — | — | US | disclosed |