Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465290 | 0.89 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11472781 | 0.88 | LMNA (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11472245 | 0.85 | CCKBR (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11474515 | 0.85 | CASP6 (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11464229 | 0.84 | CCKAR (0.39) | GABRA1GABRA5GABRA3OPRK1CCKBR | |
| SCHEMBL11471406 | 0.84 | OPRK1 (0.52) | OPRK1CCKBRGHSRLMNANR1I2 | |
| SCHEMBL11469674 | 0.83 | CCKBR (0.66) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11465323 | 0.75 | ACHE (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11072521 | 0.75 | CCKBR (0.63) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11481288 | 0.74 | OPRK1 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232016-A | 3-Fluorobenzodiazepines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-11-04 | — | — | US | disclosed |