Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | MMP16 | P51512 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473205 | 0.83 | MAPK1 (0.52) | HSD17B10KEAP1NFE2L2SMN1; SMN2RXFP1 | |
| SCHEMBL14470257 | 0.77 | ALDH1A1 (0.69) | KDM4ECA12CA9TAS2R14LMNA | |
| SCHEMBL29965637 | 0.77 | ALDH1A1 (0.55) | KDM4EHSD17B10SMN1; SMN2TAS2R14RXFP1 | |
| SCHEMBL4771204 | 0.76 | KEAP1 (0.66) | KDM4EHSD17B10KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL5450808 | 0.75 | ALDH1A1 (0.62) | KDM4ELMNAHTTALDH1A1 | |
| SCHEMBL9302981 | 0.74 | NR1H3 (0.61) | CA12CA9TAS2R14LMNAHTT | |
| SCHEMBL753112 | 0.73 | AKR1B1 (0.55) | ALDH1A1 | |
| SCHEMBL11473046 | 0.73 | MEN1 (0.67) | CA12CA9SMN1; SMN2LMNAHTT | |
| SCHEMBL30721053 | 0.73 | KEAP1 (0.54) | KDM4EHSD17B10KEAP1NFE2L2CA12 | |
| SCHEMBL11603483 | 0.72 | RECQL (0.59) | KDM4EHSD17B10KEAP1NFE2L2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198506-A | INTERMEDIATES FOR THE CORRESPONDING 3-SUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4151352-A | CEPHALOSPORINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4082912-A | ANTIBACTERIAL | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |