Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179999 | 0.69 | HSD11B1 (0.48) | ALDH1A1HTR6HSD11B1GAA | |
| SCHEMBL10180538 | 0.67 | PTGS2 (0.49) | ALDH1A1HSD11B1GAA | |
| SCHEMBL11469736 | 0.65 | MAPT (0.45) | ALDH1A1HTR6GAA | |
| SCHEMBL636190 | 0.64 | GAA (0.39) | HTR6HSD11B1GAAMMP2MMP9 | |
| SCHEMBL24805470 | 0.64 | TRPA1 (0.38) | LMNAGAA | |
| SCHEMBL23587290 | 0.61 | CNR1 (0.33) | — | |
| SCHEMBL13210401 | 0.61 | HSD11B1 (0.62) | ALDH1A1HTTHTR6HSD11B1GAA | |
| SCHEMBL10180872 | 0.60 | HSD11B1 (0.54) | ALDH1A1HTTHTR6HSD11B1 | |
| SCHEMBL28613182 | 0.59 | MYC (0.32) | LMNA | |
| SCHEMBL27242007 | 0.59 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206140-A | INSECTICIDES, ANTHELMINTICS | ROUSSEL UCLAF (FR) | 1980-06-03 | — | — | US | disclosed |
| US-4101574-A | Cyclopropanecarboxylic acid chlorides | ROUSSEL UCLAF (FR) | 1978-07-18 | — | — | US | disclosed |
| US-3997586-A | Cyclopropanecarboxylic acids and esters | ROUSSEL-UCLAF (FR) | 1976-12-14 | — | — | US | disclosed |