Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14129949 | 0.83 | CYP1A2 (1.00) | CYP2D6CYP2C9CYP1A2CYP2C19HRH1 | |
| SCHEMBL11484688 | 0.78 | TBXAS1 (0.68) | CYP2D6CYP2C9CYP1A2CYP2C19TBXAS1 | |
| SCHEMBL9744374 | 0.77 | ALDH1A1 (0.57) | HTR2AOPRM1ADORA3HTR7SIGMAR1 | |
| SCHEMBL10508433 | 0.75 | HRH2 (0.63) | HTR2AOPRM1ADORA3HTR7SIGMAR1 | |
| SCHEMBL9819864 | 0.74 | SIGMAR1 (0.69) | CYP2C19HTR2AOPRM1ADORA3HTR7 | |
| Hydrochloric Acid SCHEMBL10509615 | 0.74 | HRH1 (0.61) | HTR2AOPRM1ADORA3HTR7SIGMAR1 | |
| SCHEMBL9523895 | 0.73 | CYP2C19 (0.60) | CYP2D6CYP2C9CYP1A2CYP2C19LSS | |
| SCHEMBL7404987 | 0.73 | MAPT (0.63) | CYP2D6CYP2C9CYP1A2CYP2C19TBXAS1 | |
| SCHEMBL10562129 | 0.72 | LSS (0.60) | CYP2D6CYP2C9CYP1A2CYP2C19HRH1 | |
| SCHEMBL28108298 | 0.72 | CYP3A4 (0.65) | CYP2D6CYP2C9CYP1A2CYP2C19TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061450-B1 | METHODS OF MODULATING CELL PROLIFERATION AND CYST FORMATION IN POLYCYSTIC KIDNEY AND LIVER DISEASES | MEDICAL COLLEGE WISCONSIN INC (US) | 2017-04-19 | — | — | EP | disclosed |